Histomorphologic and Histomorphormetric Changes of the Fallopian Tube of the Female Wistar Rat Following Induced Physical and Oxidative Stress

The hypothalamo-pituitary-adrenal axis exerts profound multilevel inhibitory effects on the reproductive system. But it has remained contentious how these connections influence reproduction, especially if vision is impaired or there is a subsisting stress condition. Many works have been carried out on the male reproductive tract of various rats without corresponding work on the female. Even those carried out on the female are on the Biochemical parameters. The fallopian tube is one of the most important organs of the female reproductive system needed for viable and optimal fertility. This is because it is not only needed for the transportation of the ova and spermatozoa but also the fertilized zygote. This oviduct is common to both the female humans and the female Wistar rats. This work is aimed at studying the microscopic disposition of the fallopian tube in both normal and stressed conditions. Obtained results can be used by future Researchers and various Health Professionals as foundation data. The experiment involved 40 matured female Wistar rats which were grouped into four groups of ten each after acclimatization: Group1 is the control, Group 2 is the monoenucleated, Group 3 is the bilateral enucleation and Group 4 is the alcohol administered rats. After sacrificing the rats and harvesting the fallopian tubes, the following parameters were measured: Diameters of the fallopian tubes, Lengths of the fallopian tubes, Histomorphology of the fallopian tubes, Weights of the rats. The results showed that oxidative stress caused various degrees of nuclear damage in the fallopian mucosa compared to the enucleation and control groups. And there were no changes in the mean weights of the rats and mean lengths of the fallopian tubes in all the groups.

Key Words: Histomorphology, Histomorphometry, Fallopian Tube, Physical stress, Oxidative stress