Protective Effect of Aloe Barbadensis Miller Leaf Gel on the Reproductive System of Adult Male Wistar Rat

The medicinal and therapeutic effects of Aloe Vera has been widely studied. This study investigated the effects of Aloe Vera leaf gel (AVG) on semen parameters and reproductive hormone of Wister rats. Twenty adult male wister rats weighing 120-150grams were divided into 4 groups. Group A received feed and distilled water, Group B, C and D received oral doses of 100mg/kg b.wt. of Aluminium chloride (AlCl ), 100mg/kg b.wt. of Aluminium chloride 3 and 600mg\kg b.wt. of aloe vera extract, 100mg/kg b.wt. of Aluminium chloride and 5mg/kg b.wt. of vitamin C respectively for 30 days. The rats were sacrificed on the 30th day, the testes excised, and processed for histological and biochemical analysis. The results showed that the administration of AVG tends to ameliorate the testicular cytoarchitectural and histomorphological distortion in rats induced with AlCl at the same time significantly 3 enhancing the level of reproductive hormone. Conclusively, AVG offers antioxative effect on the testes by protecting the structural integrity of the testes as well as improving the reproductive hormones

Key Words: Aloe Barbadensis Miller, Reproductive Hormones, Semen parameters, Wistar Rats