Histological Observation of the Healing Effect of Camwood Ointment on Burnt Skin of Rabbits

Burn injury is one of the main causes of death by injury worldwide and healing of burn is still a challenge in modern medicine. Burn can happen in any area and causes dominant changes in the quality of normal tissues. In present studies we investigated the healing effect of camwood ointment on a second degree burn wound in rabbit.7 local rabbits were used in this study. The rabbits were randomly divided into 4 groups. After creating a second degree burn wound on the dorsum of the rabbits, group II, III, IV were treated with tropical application camwood ointment. Visual observation and histopathological examination were performed on days 35 of post-burn induction. At day 15, it showed moderate hyperplastic cells and koilocytosis. At day 25, it showed stratified squamous epithelia cells and proliferation of immature hair follicle and at day 35, it showed normal histology and matured hair follicles. Physically and histologically the rabbit showed gradual and progressive healing.

Key Words: Burn, camwood, histopathology, hair, follicles