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Histological and Hormonal Assessment of the Testes of Albino Wistar Rats Administered with Aqueous Ricinus Communis Linn Leaves Extract

Fischer CE, Ujah WO, Makanjuola VO, Oluwayinka PO

Histological and Hormonal Assessment of the Testes of Albino Wistar Rats Administered with Aqueous Ricinus Communis Linn Leaves Extract

People are becoming more and more dependent on herbal products rather than the chemical drugs due to their residual effects on the long run. The individual parts of plant that forms herbs like the seed, seed oil, leaves and the roots showed their importance in pharmacology. Ricinus Communis Linn is a specie from the family Euphorbiaceous, this plant is reported to possess antioxidant, anti-inflammatory, anti-diabetic, central analgesic, antitumor, antinociceptive, anti-asthmatic activity and other medicinal properties. These activities of the plant are due to the presence of important phytochemical constituents like flavonoids, glycosides, alkaloids, steroids, terpenoids etc. Twenty (20) albino wistar rats weighing 118g- 190g were grouped randomly into four groups. With the aim to assess the testes of albino wistar rats treated with Aqueous Ricinus communis linn extract histologically and check fertility potentiate of the semen parameters. Control Group were given only food with water 31days, Group A (low dose), Group B (Medium dose), Group C (High dose), were administered with 200mg/kg, 400mg/kg, 800mg/kg Aqueous Ricinus Communis linn for 31days respectively. Evaluation of body weight, histology of the testes and hormonal analysis were conducted. The data was analysed using ANOVA. Results show significant increase in male reproductive hormone across the experimental group when compared to the control group.

Key Words: Histology, Hormonal Assessment, Testes, Ricinus Communis Linn, Wistar Rat

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