EFFECTS OF CHEMICAL RIPPENING AGENT ON MATERNAL AND FOETAL LIVER OF WISTAR RAT

The aim of this study is to investigate the effects of calcium carbide ripened banana on the histological parameters of maternal and foetal liver in Wistar rats. Unripe bananas were subdivided into four groups; with three artificially ripened, using calcium carbide and one ripened via non artificial means. The pulp of these fruits were mixed with pelletized feeds and orally administrated to the Wistar rats for three weeks during and before pregnancy. Histological analysis was carried out on two groups of female wistar rats receiving different doses of calcium. Results show an infiltration of inflammatory cells, moderate congestion of hepatic vessels, distortion of hepatic tissues and architecture, before and during pregnancy. While further examination during pregnancy revealed moderate congestion of hepatic vessels, distortion of hepatic tissues and architecture, etc. Findings from this study suggest that consumption of calcium carbide ripened bananas is causing changes in the histological profiles of pregnant women. This may eventually result in severe health hazards and liver damage

Key Words: Histological, Maternal and foetal liver, Calcium carbide, Ripening, Banana, Wistar rats