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Volume 15, Number 2, Year 2024

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Mary Oluwatobiloba Adedigba , Adeshina Oloruntoba Adekeye , Ephraim Samuel Jen , Kehinde S. Olaniyi , Oluwatosin Olalekan Ogedengbe

Lycopersicon esculentum Attenuates Oxidative Stress and Hormonal Dysregulation in Letrozole-induced Polycystic Ovarian Syndrome Rat Model

Polycystic ovarian syndrome (PCOS) is the primary culprit behind anovulatory infertility and is one of the most prevalent endocrine disorders affecting women of childbearing age. The aim of the study was to explore the impact of Lycopersicon esculentum isolate on PCOS induced by letrozole in fem...

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Abdulrahim Halimat Amin, Fatoki John Olabode , Oyewo Emmanuel Bukoye , Nafiu Abdulrazaq Bidemi , Omeiza Noah Adavize, Adekunle Adeniran Sanmi

Dyslipidemic Prospective of Levonorgestrel in the Selected Central Compartments of the Liver, Kidney and Heart

Levonorgestrel, a dedicated emergency contraceptive, is prone to abuse by women of reproductive age group. We evaluated the modulatory effects of varying and repeated doses of the drug on lipid profiles in female rats. Twenty adult female Wistar rats were randomized into four groups. The normal ...

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Cancer is a multifactorial disease caused by combined genetic and non-genetic changes. Breast cancer being the second leading cause of death in women. A large percentage of known anticancer medicines are derived from various plant species. Dennettia tripetala has been found to contain vitamins, ...

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Kudighe P. Udoh , Akpan U. Ekanem , Utomobong U. Akpan , Eno-Obong I. Bassey , Ekaette P. Akpan

Costus afer Stem Juice Extract Enhances the Expression of HAS3 during the Wound Healing Process

Among its various applications, the stem juice of Costus afer has gained attention in the scientific community for its potential in tissue repair and regeneration. This study was carried out to assess the expression of hyaluronic acid synthase 3 (HAS3) in wounds treated with C. afer stem juice e...

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Ukpai C. J. , Eweoya O. , Abue A. , Okolo R. U , Onwih E.

Evaluating the Prevalence of Elongated Styloid Process in Dry Human Skulls

Styloid process is a bony projection from the inferior part of the petrous temporal bone of the skull. The research aimed to study the styloid process structure and evaluate the prevalence of elongated styloid processes in dry skulls collated by the Department of Anatomical Sciences University o...

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Abdulfattah Moisule Ganga , Maryam Isa Sharif , Lawan Hassan Adamu , Rabiu Inuwa Fage

Relationship between Cephalic Anthropometry and Somatotype among Adolescents of Hausa Ethnic Group in Kano Metropolis, Nigeria

Anthropometric studies are very important areas for craniofacial surgery and syndromology. Surgeons use these measurements to understand the unique features of a patient's face, head and body, helping them tailor their surgical approaches for optimal results. It aids in achieving aesthetic and f...

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Exposure to aluminium is associated with neurotoxicity, affecting various parts of the nervous system. The study investigated the neuroprotective potential of ethanolic fruit extract of Phoenix dactylifera (EFPD) and melatonin against aluminium chloride (AlCl3)-induced neurotoxicity in male adul...

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Adana Misturah Yetunde, Towoju Alaba Magrette, Alade Oluwadamilola Esther, Oluwasegun Blessing Olaitan, Adewale David Adebayo, Onigbolabi Oluwafemi Gideon, Ajao Moyosore Salihu

Comparative Analysis of the Protective Potentials of Nigella sativa and Lepidium meyenii on Alcohol-induced Testicular Toxicity in Adolescent Wistar Rats

Alcohol, a psychoactive drug, is soluble in both water and lipids, due to which it can diffuse to all tissues and affect the normal functioning of the body. Gonadal toxicity is reported as one of the side effects of its long-term consumption. This study examined the possible comparable protectiv...

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Animal models of cerebral ischaemia make a significant contribution to the knowledge of the pathogenesis of stroke and its methods of management. Many treatments have failed to reduce neuronal injury in cerebral ischaemia, prompting the exploration of new treatment models. The purpose of this st...

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Exposure to chronic cigarette smoking during pregnancy into infancy results in numerous morphological and behavioral consequences in infants, children, and adolescents. Cigarette smoke is a reproductive toxicant, demonstrating a strong relationship between smoking and impaired fertility. This st...

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Heavy metal exposure is a global health problem and their presence in our environment has been greatly increased by industrial activities over the past century. Manganese is an essential trace metal in the body. However, exposure to elevated levels is neurotoxic, leading to manganism, a Parkinso...

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Nasidi A, Mustapha M, Sabo HL, Abdullahi I, Babankanwa AH, Ibrahim T, Ladan MB, Idris M, Bello SA, Ahmed Abdullahi UA, Shaaba JB

Association between Handedness, Digit Ratio and Personality Traits among Adult Hausa Ethnic Group in Jigawa State, North Western Nigeria

This study explored the relationship between handedness, 2D:4D ratio, and personality traits among the Hausa ethnic group in Jigawa State, Nigeria. Data from 500 participants aged 18-30 were analysed using a cross-sectional design and simple random sampling, confirming Hausa ethnicity and Nigeri...

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Kareem SB, Muyideen MK, Ajiboye AA, Imam A, Ibrahim A, Alabi AS, Ajao MS

Sex Determination Using Tali Bones

The talus is an important bone used in forensic and archaeological cases for the determination of the sex of human remains because it is a preservational favored bone of the body. The study is designed to take the measurements and dimensions of dry tali to determine the sex as well as the sides ...

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Monodora myristica and Xylopia aethiopica have been commonly used as spices for decades, both in culinary and medicinal contexts. This study aimed to assess the effect of aqueous extract of Monodora myristica and Xylopia aethiopica on the histology of the pancreas of adult albino Wistar rats. Tw...

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Aliyu Sabo Aliyu , Nana-Asmau Hassan , Awan Stephen Kasham , Ahmad Ahmad Gaya , Maryam Isa Sharif , Abdullahi Gudaji , Rilwanu Bello , Ali Bala Umar

Histological Effects of Aqueous Allium sativum Bulb Extract on Monosodium Glutamate-induced Hepatotoxicity in Guinea Pigs

Monosodium glutamate (MSG) is among the most common food additives in the developing world and is commonly used as a flavor enhancer. It contains glutamic acid, one of the naturally occurring amino acids that the body transforms into glutamate. Allium sativum (Garlic) has tremendous pharmacologic...

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Misturah Yetunde Adana, Edidiong Nnamso Akang, Offor Ugochukwu, Simeon Eche , Edwin Coleridge Stephen Naidu , Onyemaechi Okpara Azu

Naringenin Modulates Sertoli Cell Dysfunction and Altered SCF/c-kit Ligand System in the Setting of Combination Antiretroviral Therapy

Combination Antiretroviral Therapy (cART) has been shown in previous studies to induce histopathological changes in the testes. An essential function of the c-kit signalling system is to control cell survival, proliferation, differentiation, and death. Consequently, certain male infertility may ...

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Anthony Bol Kon Giet, Olatunji Sunday Yinka, Sylvia Santos

Case Report: A Large Cadaveric Simple Hepatic Cyst

Simple hepatic cysts are the most frequent forms of liver cysts, often filled with clear or yellow fluid. They are usually asymptomatic and are typically diagnosed in adulthood. Their prevalence however varies across populations. Ultrasound and serological tests are the primary diagnostic tools ...

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Population-specific facial anthropometry is essential for cultural esteem, preservation of ethnicity, and advances in reconstructive medicine. This study focuses on craniofacial indices in students of Yoruba lineage. Using a questionnaire, biodata were collected from 2109 participants, aged 18 t...

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One neuroanatomical measure found to allometrically scale the body is brain's size. Species with larger brains relative to body are better complex information processors. We compared absolute brain weight (ABW), generated regression formulae and determined intelligence level in each age group of ...

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Felix E. Ehidiamhen , Stanley E. Ogbata , Godson O. Eze , Martins A. Nnoli , Olushola O. Jegede , Cornelius C. Chukwuegbo , Modupeola O. Samaila , Lateef A. Odukoya

Histologic Variants of Cutaneous Squamous Cell Carcinoma Diagnosed in a Tertiary Health Facility in Southeast Nigeri

Cutaneous squamous cell carcinomas are tumours originating from cutaneous keratinocytes and they are among the most commonly encountered skin cancers. This study analysed the various histologic variants of cutaneous Squamous Cell Carcinoma (cSCC) diagnosed in the hospital. The study was a descri...

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The double-spurred Francolin is a feral bird and remains undomesticated with very little known about its reproductive capability. This study aimed to know the structural integrity of its testis. Birds (n=5), were obtained during the dry and rainy seasons from their natural habitat in Kano, stabi...

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